Michael Narkewicz and Zachary Sellers - Liver Disease in Cystic Fibrosis

In this episode, hosts Drs. Jason Silverman and Temara Hajjat talk to Drs. Michael Narkewicz and Zachary Sellers about screening, evaluation and management of children with cystic fibrosis with hepatobiliary involvement and advanced CF liver disease. We review the new consensus recommendations paper published in the May issue of Hepatology (open access link below). 
 
Dr. Narkewicz is a pediatric gastroenterologist and transplant hepatologist at Children’s Hospital Colorado and professor of pediatrics at the University of Colorado with a strong clinical and research interest in cystic fibrosis and in particular on liver disease in cystic fibrosis who has presented and published extensively in this area over his career.

Dr. Sellers is a pediatric gastroenterologist, Adjunct professor and physician-scientist at Stanford with clinical interests in the GI manifestations of cystic fibrosis and pancreatitis in children who has worked with the INSPPIRE consortium and has presented and published widely on CF and liver disease in CF.

Learning objectives:

1. Define cystic fibrosis with hepatobiliary involvement (CFHBI) and advanced cystic fibrosis liver disease (aCFLD)
2. Outline recommendations for screening and evaluation for patients with CF and liver involvement
3. Outline the recommendations for management of patients with CF and liver involvement

Papers discussed in this episode (both are open access!:

1. Cystic fibrosis screening, evaluation, and management of hepatobiliary disease consensus recommendations
2. Towards a Standardized Classification of the Hepatobiliary Manifestations in Cystic Fibrosis (CFHBI): A Joint ESPGHAN/NASPGHAN Position Paper